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Similarity Search Applications in Medical Images

Dissertation of Marisa Petri
at the Fakultät für Mathematik, Informatik und Statistik of the Ludwig-Maximilians-Universität München.
Written at the Lehr- und Forschungseinheit für Datenbanksysteme.

Supervisor: Prof. Dr. Hans-Peter Kriegel
Second Reviewer: Prof. Dr. Mario Nascimento
Submitted at: 18th July 2011
Defense at: 17th January 2012

Abstract

The advances in medical imaging have enabled the large-scale generation of medical image data in hospitals and private clinics. While taking a high-resolution scan of a troubling body part has been rather exceptional in the past, it is now common practise for a large variety of patient conditions.

The research project THESEUS MEDICO aims at the re-organization of medical picture archiving and communication systems (PACS) such that they can be efficiently queried for more advanced image meta-data than a small set of common identifiers. As a complement to keyword-based retrieval queries, MEDICO also offers a variety of content-based image retrieval (CBIR) applications.

Two use cases employing CBIR techniques for answering clinical queries on Computed Tomography (CT) scans have been developed in the course of this thesis. The first application provides a standardized body coordinate system using image-based landmarks and further image information for automatically providing an anatomical context for any given scan region and for greatly accelerating retrieval queries. The second application is a more direct form of CBIR, enabling the specification of a visual query template which is used for retrieving similar image patterns.

This thesis introduces a variety of newly-developed similarity search components and it evaluates the generated medical search framework at the example of the two search applications.

Document

The thesis is available at the university library in electroniv form.
Link to the elektonic version at the library

Acknowledgments

This work was financed by the German Federal Ministry of Economics and Technology under the grant number 01MQ07020 within the research program THESEUS MEDICO. The responsibility for this publication lies with the author.


logo: Supported by BMWi


BibTeX Citation

@PHDTHESIS{Petri2011,
    author    = {Petri, Marisa},
    title     = {Similarity Search Applications in Medical Images},
    school    = {Ludwig-Maximilians-Universit\"{a}t M\"{u}nchen},
    year      = {2011},
    type      = {Doktorarbeit},
    address   = {Munich, Germany},
    month     = {7}
}

Relevant Publications

2012
9Hans-Peter Kriegel, Marisa Petri, Matthias Schubert, Michael Shekelyan, Michael Stockerl
Efficient Similarity Search on 3D Bounding Box Annotations
In Proceedings of the SPIE Medical Imaging Conference 2012: Advanced PACS-based Imaging Informatics and Therapeutic Applications (SPIE), San Diego, CA: 8319-10, 2012.
2011
8Alexander Cavallaro, Franz Graf, Hans-Peter Kriegel, Matthias Schubert, Marisa Thoma
Region of Interest Queries in CT Scans
In Proceedings of the 12th International Symposium on Spatial and Temporal Databases (SSTD), Minneapolis, MN: 56–73, 2011.
7Florian Stegmaier, Mario Döller, Kai Schlegel, Harald Kosch, Sascha Seifert, Martin Kramer, Andreas Hutter, Marisa Thoma, Hans-Peter Kriegel, Alexander Cavallaro
Generische Datenintegration zur semantischen Diagnoseunterstützung im Projekt THESEUS MEDICO
In Proceedings of the 41st Jahrestagung der Gesellschaft für Informatik: Datenmanagement und Interoperabilität im Gesundheitswesen, Berlin, Germany: 41–55, 2011.
6Sascha Seifert, Marisa Thoma, Florian Stegmaier, Matthias Hammon, Martin Kramer, Martin Huber, Hans-Peter Kriegel, Alexander Cavallaro, Dorin Comaniciu
Combined semantic and similarity search in medical image databases
In Proceedings of the SPIE Medical Imaging Conference 2011: Advanced PACS-based Imaging Informatics and Therapeutic Applications, Lake Buena Vista, FL, 7967: 7967–2, 2011.
2010
5Marisa Thoma, Hong Cheng, Arthur Gretton, Jiawei Han, Hans-Peter Kriegel, Alex Smola, Le Song, Philip S. Yu, Xifeng Yan, Karsten M. Borgwardt
Discriminative Frequent Subgraph Mining with Optimality Guarantees
Statistical Analysis and Data Mining, 3(5): 302–318, 2010.
4Tobias Emrich, Franz Graf, Hans-Peter Kriegel, Matthias Schubert, Marisa Thoma
Similarity Estimation using Bayes Ensembles
In Proceedings of the 22nd International Conference on Scientific and Statistical Database Management (SSDBM), Heidelberg, Germany: 537–554, 2010.
3Tobias Emrich, Franz Graf, Hans-Peter Kriegel, Matthias Schubert, Marisa Thoma, Alexander Cavallaro
CT Slice Localization via Instance-Based Regression
In Proceedings of the SPIE Medical Imaging Conference 2010: Image Processing (SPIE), San Diego, CA, 7623: 762320, 2010.
2009
2Marisa Thoma, Hong Cheng, Arthur Gretton, Jiawei Han, Hans-Peter Kriegel, Alex Smola, Le Song, Philip S. Yu, Xifeng Yan, Karsten M. Borgwardt
Near-optimal supervised feature selection among frequent subgraphs
In Proceedings of the 9th SIAM International Conference on Data Mining (SDM), Sparks, NV: 1075–1087, 2009.
2008
1Karsten M. Borgwardt, Xifeng Yan, Marisa Thoma, Hong Cheng, Arthur Gretton, Le Song, Alex Smola, Jiawei Han, Philip S. Yu, Hans-Peter Kriegel
Combining near-optimal feature selection with gSpan
In Proceedings of the 6th International Workshop on Mining and Learning with Graphs (MLG), Helsinki, Finland, 2008.
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